Exploring the role of the enteric nervous system on myelination during early life: modulation of gut microbiota and development of the microbiota-gut-brain axis

During infancy neural axons rapid myelination, slowly consolidates spatiotemporally until adulthood to ensure neurotransmission and brain functions. The prefrontal cortex, undergoing later myelination in new-born, is affected by neonatal intestinal microbial status, and highly implicated in the development of brain in early life.